Program Thursday April 7th 2022
| 09:00 | Welcome & Coffee | |
| 09:40 | Opening by Pascal Jonkheijm | |
| Session I - Chair: Leendert van den Bos |
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| 09:45 | KEYNOTE I: Frank Glorius- Westfälische Wilhelms Universität Münster (Germany) On discovery and sensitivity in (photo)catalysis |
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| 10:35 | Dennis Wander (LU) A Library of Synthetic Doxorubicin Derivatives for Improved Anticancer Treatment |
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| 10:50 | Martien Würdemann (VU) The Forgotten Pyrazines: Exploring the Dakin West reaction |
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| 11:05 | Bianca van Tol (LUMC) Development of neutron-encoded ubiquitin chains to study deubiquitinase activity in presence of all eight ubiquitin linkages |
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| 11:20 | Sam Moons (RU) Selective N-Deacetylation and functionalization of Aminosugars |
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| 11:35 | Lunch & ALV (ALV starts at 12.30) | |
| Session II - Chair: Kim Bonger/Patrick Uiterweerd | ||
| 13:00 | KEYNOTE II: Yimon Aye - Ecole Polytechnique Fédérale de Lausanne (Switzerland) Lighting the way: Function-guided proximity mapping & precision signaling interrogations open up new opportunities |
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| 13:50 | KEYNOTE III: Luisa De Cola - Universita degli Studi di Milano Statale (Italy) Releasing or capturing that is the question. Porous molecular materials |
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| 14:40 | Floris van Delft (Synaffix) Targeted Cancer Therapy with Best-in-Class Antibody-Drug Conjugates (ADCs) based on Site-Specific Conjugation to Antibody Glycan |
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| 14:55 | Coffee/Tea | |
| Session III - Chair: Mark Borst | ||
| 15:25 | Peter Cossar (TUE) A reversible covalent cross-linking approach for stapling of the 14-3-3/ERRγ protein complexes |
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| 15:40 | Tobias Schnitzer (TUE) Supramolecular polymers: a new synthesis strategy for complex molecular systems |
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| 15.55 | Seino Jonkees (VU) Dehydroalanine as a handle for chemical modification of peptides in mRNA display |
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| 16.10 | Markus Kwakernaak (TUD) Room temperature synthesis of aliphatic perylene diimides facilitated by amic acid solubility |
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| 16:25 | KEYNOTE IV (online): Martin D. Burke - University of Illinois at Urbana-Champaign (USA) Imagine a world where everyone can make molecules |
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| 17:15 |
Drinks
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| 18:30 | Dinner (registration necessary) | |
Program Friday April 8th 2022
| 08:30 | Coffee | |
| Session V - Chair Eelco Ruijter | ||
| 09:00 | KEYNOTE V (online): Phil Baran - Scripps Research Institute (USA) Simplifying Synthesis with Electricity |
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| 09:50 | Georgios Alachouzos (RUG) Computational Design, Synthesis and Photochemistry of Cy7-PPG, an Efficient NIR-activated Photolabile Protecting Group for Therapeutic Applications |
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| 10.05 | Niels Reintjens (RUG) Protection group-free reductive chlorination and thiolation of glycosides via trityl hydrazones |
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| 10:20 | Jeya Prathap Kaniraj (RUG) Two in One: Asymmetric Total Synthesis of the Mycobacterial Glycolipids Pentaacyl Trehalose (PATs) |
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| 10.35 | Massimo Giannerini (Janssen) High-Throughput experimentation enabling rapid process optimization of an RSV drug candidate |
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| 10:50 | Coffee | |
| Session V - Chair: Pascal Jonkheijm | ||
| 11:20 | KEYNOTE VI: Alexander Dömling (RUG) Automation + Miniaturization = Acceleration |
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| 12:10 | KEYNOTE VII: Sabine Flitsch - University of Manchester (UK) Cascading biocatalysis for organic synthesis |
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| 13:00 | Announcement winner The Backer-KNCV prize 2022 - Adri Minnaard | |
| 13:05 | Lunch | |
| Session VI - Chair: Tom Wennekes | ||
| 14.15 | Matthijs ter Harmsel (RUG) A catalytically active small organic molecule pH oscillator |
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| 14:30 | Dennis Löwik (RU) Theranostic PSMA ligands for intraoperative multimodal imaging and photodynamic therapy of prostate cancer |
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| 14:45 | Ruben Andringa (RUG) Total synthesis of dissectol A |
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| 15:00 | Yara Huppelschoten (LUMC) Chemical synthesis of a GFP Nanobody |
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| 15:15 | KEYNOTE VIII (online): Vy M. Dong - University of California Irvine (USA) Choose your own adventure in metal-hydride catalysis |
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| 16:05 | Closing followed by drinks | |
